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Akram N Salah¹, Youssef A Doghish², Shaimaa O Abbass³

¹Microbiology and Immunology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.

Folia microbiologica

|October 11, 2025

概括

人口微生物组会影响健康,而口腔疾病则会导致口腔疾病. 新兴的微生物组疗法,如益生菌和细菌菌体,为恢复平衡和治疗感染提供了新的途径.

科学领域:

口腔微生物组研究
微生物生态学微生物生态学
宿主-微生物相互作用

背景情况:

人的口腔内有复杂的微生物群,对健康至关重要.
微生物失衡 (失生症) 与口腔疾病 (如牙和牙周炎) 有关.
病原体联盟,如红色复合体,通过毒性和生物膜驱动疾病的进展.

研究的目的:

审查了解口腔微生物组失调的最新进展.
探索新兴的基于微生物的治疗方法,治疗口腔疾病.
突出口腔健康干预中新策略的潜力.

主要方法:

审查当前的微生物组研究,专注于致病机制.
分析新兴的治疗策略,包括益生菌,后生菌,掠食性细菌和细菌菌体.
检查口腔微生物群移植作为一种治疗方式.

主要成果:

益生菌 (例如,Streptococcus salivarius,Lactobacillus spp.) 的使用是非常重要的. 减少斑块,炎症和病原体,调节免疫力.
后生物质提供了类似的好处,提高了安全性和稳定性.
捕食性细菌 (例如,Bdellovibrio bacteriovorus) 和细菌菌体显示出有针对性消除病原体的潜力.

结论:

基于微生物组的疗法为传统抗微生物治疗提供了有希望的替代方案.
这些策略旨在恢复微生物平衡,减少病原体,调节宿主反应.
需要进一步的研究来将这些发现转化为个性化口腔健康的临床实践.

关键词:

牙腐烂是一种牙腐烂.微生物群的治疗方法口腔疾病是一种口腔疾病.口腔微生物组是口腔的微生物组.牙周病是牙周病的一种疾病.益生菌益生菌益生菌

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