使用虚拟现实的厌恶疗法的对渴望,抑郁和自我效能的影响:在接受甲维持治疗的患者中进行的一项试点研究
Nasim Sadeghi1,2, Elham Sadat Mousavinasab3, Ehsan Sharifi4
1Department of Addiction Studies, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Brain and behavior
|October 12, 2025
概括
基于虚拟现实的厌恶疗法显著减少了对物质的渴望,抑郁症,并改善了接受美沙维持疗法的患者的自我有效性. 这种创新方法显示出提高物质使用障碍治疗结果的希望.
科学领域:
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
- 数字健康数字健康
背景情况:
- 药物使用障碍 (SUD) 构成了重大的公共卫生挑战,往往需要长期的管理策略.
- 甲维持疗法 (MMT) 是基石治疗,但复发和同时出现的心理健康问题仍然很普遍.
- 需要新的治疗方式来增强现有的MMT协议并改善患者的治疗结果.
研究的目的:
- 评估基于虚拟现实的厌恶疗法 (VRAT) 作为MMT的辅助疗法的有效性.
- 评估VRAT对减少物质渴望,缓解抑郁症状和增强自我效能的影响.
- 将VRAT与传统的心理咨询和单独的MMT进行比较.
主要方法:
- 进行了一项干预性临床试验,90名参与者 (年龄在25-55岁) 接受了MMT.
- 参与者被随机分为三个组:VRAT + MMT,心理咨询 + MMT和仅MMT.
- VRAT利用Python编程进行交互式模拟,逐渐暴露于负面刺激,认知重组和积极行为强化.
主要成果:
- 对抑郁症 (p<0.001),自我效能 (p<0.001) 和渴望 (p<0.001) 的组之间观察到显著的差异.
- 与两个对照组相比,VRAT显著降低了使用欲望/意图,渴望/负面强化以及快乐/缺乏控制.
- 与心理咨询和对照组相比,VRAT还显著降低了抑郁症,提高了自我效能.
结论:
- VRAT显示出作为SUDs的有效治疗干预措施的巨大潜力.
- 这项技术提供了一种创新,补充或替代的方法,以提高药物滥用治疗的质量和有效性.
- 需要进一步的研究来完善VRAT协议并将其整合到标准的临床实践中.
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