在TMS中监测不良影响:从受控试验到临床现实
Thomas van der Velde1, Johanna Swartswe2, Koen Schruers1
1Department of Psychiatry and Neuropsychology, Faculty of Health Medicine and Lifesciences, Maastricht University, Maastricht, the Netherlands.
Current opinion in psychology
|October 12, 2025
概括
跨磁刺激 (TMS) 是一种安全的,非侵入性的治疗方法,用于治疗抑郁症等脑部疾病. 虽然一般耐受良好,但存在潜在的风险,如头痛和罕见的发作,需要仔细监测.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 超磁刺激 (TMS) 是一种领先的非侵入性神经调节技术.
- 它被广泛用于治疗精神和神经疾病,特别是严重抑郁症.
- 尽管它有效,但了解它的风险概况对于安全的临床应用至关重要.
研究的目的:
- 综合审查与跨磁刺激 (TMS) 相关的不良影响.
- 突出监测心理副作用的重要性,如nocebo反应.
- 为了强调需要标准化报告和数据透明度,随着TMS使用的扩大.
主要方法:
- 对TMS不良事件的文献进行系统审查.
- 分析报告的副作用,包括常见的,严重的,心理和认知影响.
- 评估当前的监测实践和数据报告系统.
主要成果:
- 常见的TMS副作用包括头痛和头皮不适.
- 严重的不良事件,如发作是罕见的 (每10万次治疗每7次),并且与高危人群有关.
- 心理 (nocebo) 和轻度/短暂的认知效应需要进一步调查.
结论:
- 一般来说,TMS是安全有效的,但它带有潜在的风险,必须加以管理.
- 标准化的监控工具和透明的注册表对于安全有效的TMS实施至关重要.
- 对心理副作用的进一步研究是有必要的,以优化患者护理.
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