布鲁塞拉败血性关节炎:一个病例系列和文献综述
Saad Almohrij1, Ibrahim Bahabri2, Rayan M Alghamdi2
1College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; King Abdulaziz Medical City-Riyadh, Ministry of National Guard Health Affairs, Saudi Arabia; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Journal of infection and public health
|October 12, 2025
概括
布鲁塞拉性关节炎在沙特阿拉伯很常见,通常会影响膝盖. 虽然抗生素治疗是有效的,但许多患者经历了持久的关节功能障碍,需要持续的护理.
科学领域:
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
- 整形外科手术 整形外科手术
背景情况:
- 在全球范围内,百菌病是显著的动物性感染,骨关节干扰是常见的并发症.
- 由于布鲁塞拉菌引起的败血性关节炎是一个诊断和管理的挑战,特别是在像沙特阿拉伯这样的流行地区.
研究的目的:
- 分析布鲁塞拉败血性关节炎的临床特征,治疗和结果.
- 与其他细菌性关节炎相比,突出布鲁塞拉败血性关节炎的独特特征.
主要方法:
- 对18名患有培养确认的布鲁塞拉败血性关节炎患者的回顾性分析.
- 对患者人口统计,临床表现,实验室和成像发现,治疗和结果的审查.
- 文献审查以将发现置于背景.
主要成果:
- 研究人口主要由男性 (67%) 组成,平均年龄为59.5岁;膝盖是受影响最严重的关节 (78%).
- 常见的症状包括关节疼痛,胀和运动范围有限,59%的人发烧. 较高的炎症标志物是典型的,通常与正常的白细胞计数.
- 联合抗生素治疗 (平均105天) 和手术干预 (47%) 是常见的. 所有患者在临床上都有改善,但61%的患者有剩余的关节功能障碍.
结论:
- 布鲁塞拉败血性关节炎具有明显的临床和实验室特征.
- 延长组合抗生素治疗是有效的,但残留关节功能障碍是常见的,需要全面的治疗后护理.
- 在特有地区的早期识别至关重要,即使没有全身症状,由于可能出现单关节性关节炎.
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