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使用ESR2分子对接和超过技术,针对更年期后骨质疏松症对人参的活性成分选

Chunnan Li1, Yiying Tan1, Lu Han1

  • 1Jilin Institute of Ginseng Science, Changchun University of Chinese Medicine, Changchun 130117, China.

Journal of pharmaceutical and biomedical analysis
|October 12, 2025
PubMed
概括

像Ginsenoside Rf,Re和Rb1这样的人参化合物通过与ESR2酶相互作用,显示出治疗绝经后骨质疏松症 (PMOP) 的前景. 这项研究确定了潜在的PMOP疗法的关键活性成分.

关键词:
在ESR2中使用ESR2.人参就是一个人,人参就是一个人.分子对接是分子对接.分子动力学模拟模型在PMOP中使用PMOP.美国UHPLC-QE轨道飞行器-MS

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Bone Disorders01:29

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...