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线粒体DNA异质体的检测方法及其在癌症中潜在的单细胞应用

Tianguang Cheng1, Min Pan2, Yi Qiao1

  • 1State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Biochimica et biophysica acta. Reviews on cancer
|October 12, 2025
PubMed
概括

线粒体DNA (mtDNA) 异质体,即正常和突变mtDNA的混合物,是癌症的关键. 单细胞分析揭示了它在瘤发育和治疗耐药性方面的作用.

关键词:
癌症代谢 癌症代谢异质塑性是一种异质塑性.线粒体DNA是线粒体的DNA.序列化是指测序的使用.一个单细胞的单细胞.

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