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Updated: Jan 15, 2026

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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OTUB1通过调节胰腺β细胞中的SLC7A11 Ubiquitination来调节铁

Soyeon Yoo1,2, Dongkyu Kim1, Miyeon Kim1,2

  • 1Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|October 13, 2025
PubMed
概括

2-脱氧-d-ribose (dRib) 通过抑制OTUB1-SLC7A11通路,触发胰腺β细胞中的铁亡,导致细胞死亡. 恢复OTUB1或SLC7A11可以保护β细胞免受dRib诱导的铁亡.

关键词:
2-脱氧-d- рибо的使用.OTUB1 在线播放在 SLC7A1111 中.铁性化 (ferroptosis) 是一种在β-细胞中.

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