概括
基于加多的对比剂可以在实验室测试中导致虚假的低水平. 识别这种干扰可以防止不必要的医疗治疗,并确保准确的患者护理.
科学领域:
- 临床化学 临床化学
- 医学诊断 医学诊断 医学诊断
- 放射学 放射学是一门学科.
背景情况:
- 基于加多的对比剂 (GBCA) 经常用于MRI扫描.
- 像gadodiamide一样,GBCA可以干扰特定的实验室测试.
- 这种干扰可能导致患者测试结果不准确,特别是水平.
研究的目的:
- 报告一个人为低血症的病例,这种病例是由基于加多的对比剂引起的.
- 强调在临床实践中识别GBCA干扰的重要性.
- 突出需要适当的诊断策略的需要.
主要方法:
- 一名患者呈现出严重低血清水平.
- 最初的调查排除了标准的预分析和分析错误.
- 通过将实验室结果与最近使用的加多基对比剂相关联,解决了这种差异.
主要成果:
- 最初观察到血清度极低的临界值.
- 随后的测试显示了正常化的水平,表明这是暂时的问题.
- 低的结果归因于加多胺与甲基乙醇蓝色对比试验的干扰.
结论:
- 基于加多的对比剂的使用可以诱导人为性低血症.
- 实验室和临床团队之间的密切合作对于诊断这种干扰至关重要.
- 建议注意GBCA干扰,并考虑使用其他测定方法,如离子选择性电极.
相关概念视频
Skeleton and Calcium Homeostasis
5.8K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
5.8K
Hormones and Bone Tissue
3.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.7K
Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
1.6K
Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in calcium-dependent tissues like the SA and AV nodes. These drugs manage reentrant supraventricular tachycardia (SVT) and reduce ventricular rate in atrial flutter/fibrillation.
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
1.6K
Antiepileptic Drugs: Potassium Channel Activators
632
Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Ezogabine has gained approval as an adjunctive treatment...
632
Antiepileptic Drugs: Calcium Channel Blockers
1.1K
Calcium channel blockers, a class of antiepileptic drugs, regulate the flow of calcium ions within neurons.
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
1.1K
Imaging Studies I: CT and MRI
792
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
792


