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脊柱体内注射用于腰椎间盘和腰椎退行性磁盘疾病

Satvik Muralidhar¹, Himanshu Jain¹, Manoj Kumar¹

¹Department of Orthopedics, MM Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India.

Journal of orthopaedic case reports

|October 13, 2025

概括

外围注射类固醇注射 (ESI) 为腰椎间盘 (LDH) 和退行性椎间盘疾病 (LDDD) 提供短期的疼痛缓解. 虽然最初是有效的,但症状可能会复发,强调需要全面的管理策略.

科学领域:

疼痛管理疼痛管理
神经外科神经外科
肌肉骨系统疾病肌肉骨系统疾病

背景情况:

腰部疼痛是导致残疾的主要原因,通常是由腰椎间盘 (LDH) 和腰椎退行性磁盘疾病 (LDDD) 引起的.
这些情况导致神经炎症和压缩,导致显著的疼痛和运动能力下降.
外周注射类固醇注射 (ESI) 是一种最少的侵入性治疗选择,可以减少炎症并改善功能.

研究的目的:

在被诊断患有LDH或LDDD的患者中,评估 epidural类固醇注射 (ESI) 的短期有效性.
分析视觉模拟量表 (VAS) 疼痛评分在注射后六个月的变化.
确定影响该患者队列治疗结果的潜在因素.

主要方法:

一项前性研究涉及50名成年患者,这些患者患有由LDH或LDDD引起的腰部根系病变,并没有对保守治疗做出反应.
数据收集包括人口统计,病史,根性病变水平和VAS疼痛得分在基线和注射后3个月和6个月.
进行了统计分析,以根据诊断,性别,BMI和根性病变水平来比较结果.

主要成果:

这项研究包括50名患者 (平均年龄为47岁,66%为男性).
在ESI后3个月 (从~7到~4) 观察到疼痛显著减少 (VAS得分),在6个月后部分症状复发 (VAS~5.5).
没有发现关于性别,BMI或根细胞病变水平 (P > 0.05) 的治疗结果的统计学上显著差异.

结论:

外周注射类固醇注射 (ESI) 在减轻腰椎间盘 (LDH) 和腰椎间盘退行性疾病 (LDDD) 患者的疼痛方面表现出短期的有效性.
观察到的6个月的症状复发强调了持续管理方法的必要性.
脑电阻是疼痛管理的重要组成部分,但应纳入全面的治疗计划,以获得最佳的长期结果.

关键词:

视觉模拟尺度视觉模拟尺度退行性磁盘疾病是一种退行性磁盘疾病.外围注射类固醇注射的外围注射.腰椎椎间盘的发生疼痛管理疼痛管理根基病变是一种根基病变.

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