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Updated: Jan 15, 2026

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation
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DNAzyme-dependent Analysis of rRNA 2’-O-Methylation

Published on: September 16, 2019

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用印结核酸对脱氧核酸的修改会诱导BZ和Z形状,并改变其对酶裂变的敏感性

Suresh Lingala1, Anastasiia Fisiuk2, Michelle Stephen3

  • 1Department of Molecular, Cellular and Biomedical Sciences, City University of New York School of Medicine, 160 Convent Avenue, New York, New York 10031, United States.

ACS omega
|October 13, 2025
PubMed
概括

在生理条件下,称为"Z-诱导嵌合体" (ZImeras) 的新型印醇修饰DNA复合体可以形成像Z-DNA这样的非正规结构. 灵活的链接器使这些结构变化成为可能,为DNA结构研究和治疗提供了新的工具.

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