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Updated: Jan 15, 2026

A Patient-Derived Xenograft Model for Venous Malformation
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血管生成相关途径的体质突变和RNA聚合酶II活性在零星的大脑动脉静脉形形中

Rebeca Pérez-Alfayate1, Vanesa García-Barberán2, Isabel Casado-Fariñas3

  • 1Neurosurgical Department, Hospital Universitario Clínico San Carlos, IdISCC, Madrid, Spain.

Frontiers in neurology
|October 13, 2025
PubMed
概括

对大脑动脉静脉形形 (bAVMs) 的遗传分析揭示了血管生成和RNA聚合酶II途径的突变. 这些发现表明,转录失调有助于bAVM发育和血管不稳定.

关键词:
修复DNA的修复DNA的修复通过PI3K路径.的RNA聚合酶II.血管新生是因为血管新生.大脑动脉静脉形形内动脉静脉形形 内动脉形形这是下一代测序.身体突变是一种体质突变.

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