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在喘患者中开发和评估用于吸入器使用的药物坚持措施
Woranuch Saengcharoen1, Nisanat Nanual2, Sanguan Lerkiatbundit3
1Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Thailand.
The Malaysian journal of medical sciences : MJMS
|October 13, 2025
概括
一个新的工具,吸入器使用者的药物坚持措施 (MAM-I),有效地识别了喘患者的不坚持. 这种可靠和有效的天平有助于喘管理,通过确定需要支持的个人.
科学领域:
- 肺部医学 肺部医学
- 临床药房 临床药房
- 健康 结果 研究 研究 结果
背景情况:
- 对于评估吸入器粘附性而言,存在有限的验证尺度.
- 现有的措施往往缺乏可靠的有效性和诊断数据.
- 吸入器不粘附显著影响喘管理和患者的结果.
研究的目的:
- 为吸入器使用者开发药物坚持措施 (MAM-I).
- 评估MAM-I. 的可靠性,有效性和诊断准确性.
- 建立一个切断分数来识别喘患者的不坚持.
主要方法:
- 一项涉及145名喘患者的横截面研究.
- 参与者完成了MAM-I,MiniAQLQ和MCSDS的测试.
- 评估了可靠性 (克朗巴赫的α) 和有效性 (标准,并发,预测,构造).
- 接收器操作特征 (ROC) 曲线分析确定了使用6个月的喘控制作为黄金标准的不遵守的截止分数.
主要成果:
- 该MAM-I显示出良好的可靠性 (Cronbach的alpha在基线时为0.784,在6个月后为0.749).
- 观察到MAM-I得分与坚持,喘控制和生活质量之间存在显著的相关性 (P < 0.001).
- 截止分数小于15表示不遵守,准确度高 (93.10%),灵敏度高 (78.95%),特异性高 (98.13%).
结论:
- MAM-I是一种可靠和有效的仪器,用于评估喘中的吸入器粘附性.
- 该尺度具有有利的诊断特性,包括78.95%的灵敏度和98.13%的特异性.
- 在喘管理的临床实践中,MAM-I的截止分数为<15,是识别吸入器不粘附的有价值工具.
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