关于使用F-FDG用于PET/CT成像使用OLINDA/EXM和Geant4蒙特卡罗模拟的剂量测量评估 - - 单一中心体验

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Muhammad Zulfadhli Zaini^1,2, Nurul Ab Aziz Hashikin¹, Aminudin Said²

¹School of Physics, Universiti Sains Malaysia, Pulau Pinang, Malaysia.

The Malaysian journal of medical sciences : MJMS

|October 13, 2025

概括

这项研究评估了马来西亚F-FDG PET/CT扫描中的辐射剂量. 通过OLINDA/EXM和Geant4 MC方法确认的剂量都是安全的,符合国际标准.

科学领域:

医学成像和剂量测量
核医学物理物理

背景情况:

F-FDG PET/CT是一种至关重要的诊断工具.
精确的剂量测量对于尽量减少辐射暴露至关重要.
评估吸收剂量可以确保临床环境中的患者安全.

研究的目的:

在马来西亚IKN接受F-FDG PET/CT的患者中评估吸收的辐射剂量.
为了比较OLINDA/EXM和Geant4 MC对剂量计的模拟方法.
验证遵守国际辐射保护委员会 (ICRP) 安全标准.

主要方法:

使用OLINDA/EXM (v1.1) 和Geant4 MC (v10.6.0) 进行剂量评估.
评估了肝脏,脏和膀吸收的剂量.
在Geant4 MC中使用MIRD-5幻影和在OLINDA/EXM.中使用日本标准化的参考模型.

主要成果:

使用这两种方法计算肝脏,脏和膀的平均吸收剂量.
结果显示,肝脏和脏的情况很一致,而尿膀的情况有显著差异.
根据ICRP-128.8,被吸收的剂量被发现处于安全范围内.

结论:

对于F-FDG剂量计,OLINDA/EXM和Geant4 MC都是可靠的.
方法的选择取决于诊所的资源 (时间,计算能力).
根据安全标准,F-FDG PET/CT 在IKN的诊断使用是安全的.

关键词:

在18F-FDG中.在Geant4 MC模拟中使用Geant4 MC模拟.在ICRP中,ICRP是指ICRP.这就是 IKN IKN.美国国家癌症研究所在 MIRD5 数学幻影中.奥林达/埃克斯姆 (EXM) 的情况.

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