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Updated: Jan 15, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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在DNA损伤条件下,p53mRNA表现出类似于 рибо开关的特征

Sa Chen1, Lixiao Wang1, Laurence Malbert-Colas2

  • 1Department of Medical Biosciences, Umeå University, Building 6M, 901 85 Umeå, Sweden.

iScience
|October 13, 2025
PubMed
概括

哺乳动物的p53mRNA具有类似于 рибо开关的特性,在DNA受损后控制蛋白质合成. 一种特定的突变 (CASM22) 破坏了这种调节,影响了p53 DNA损伤反应途径.

关键词:
分子生物学分子生物学结构生物学是结构生物学.

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