对与破坏性手术出血相关的临床和经济结果的回顾性数据库分析
Mosadoluwa Afolabi1, Prathiksha N V2, Amitha Kumar3
1Global Epidemiology, Johnson & Johnson MedTech, New Brunswick, NJ, USA.
ClinicoEconomics and outcomes research : CEOR
|October 13, 2025
概括
破坏性手术出血,即使是用静血剂,也显著增加了手术室的时间,再入院,死亡率和大手术的成本. 这凸显了对更好的干预措施的迫切需要,以管理这些程序中的出血并发症.
科学领域:
- 外科手术 手术手术
- 医疗保健管理的管理
- 患者安全 患者安全
背景情况:
- 干扰性手术出血使手术过程复杂化,尽管使用了静血剂.
- 这项研究侧重于减肥,结直肠,脊椎,全关节整形术 (THA) 和全膝关节整形术 (TKA) 的手术.
研究的目的:
- 评估破坏性手术出血的临床和经济结果.
- 确定出血并发症对患者康复和医疗保健资源利用的影响.
主要方法:
- 分析了2019年接受5项特定手术的高级医疗保健数据库患者 (≥18岁) 的分析.
- 在有和没有破坏性出血的患者之间比较临床和经济结果 (OR时间,再入院,死亡率,ICU停留,呼吸机使用,成本,LOS).
- 根据基线特征调整的多变量分析.
主要成果:
- 10.8%的患者经历了破坏性出血.
- 在大多数手术中,破坏性出血显著增加了手术室时间,90天再入院,住院患者死亡率,ICU入院/持续时间和呼吸机使用.
- 所有五种手术的医院费用和住院时间 (LOS) 都显著增加.
结论:
- 干扰性出血会造成相当大的临床和经济负担.
- 显著需要改进的干预措施,以预防和管理手术出血并发症.
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