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Updated: Jan 15, 2026

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
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骨细胞通过Wnt-TGFβ信号轴产生RANKL,用于骨细胞形成

Yujiao Liu1,2, Lizhou Zhao1, Molin Li1

  • 1Laboratory of Skeletal Development and Regeneration, Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China.

International journal of biological sciences
|October 13, 2025
PubMed
概括

骨细胞通过Wnt-TGFβ信号通路控制RANKL表达来调节骨的再吸收. 这一发现阐明了骨重塑和骨质细胞分化中的一个关键机制.

关键词:
骨质细胞是一种骨质细胞.兰克尔 (Rankl) 是一个名字.在TGFβ中,TGFβ是TGFβ.在Wnt/β-catenin中使用.骨质细胞生成 (osteoclastogenesis) 是一个

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