患有2型糖尿病的老年人认知虚弱的风险因素分析:一个横截面研究
Qingjuan Ren1, Shu Niu2, Lei Zhi1
1Department of Geriatrics, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, China.
Frontiers in aging neuroscience
|October 13, 2025
概括
认知虚弱 (CF) 影响24.3%的2型糖尿病 (T2DM) 的老年人. 脑血管疾病和外围动脉疾病增加了CF风险,而高等教育和晚期糖尿病发病是保护性的.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 神经学 神经学
背景情况:
- 认知虚弱 (CF) 是一种日益关注的老年人与2型糖尿病 (T2DM).
- 肌痛性肌痛包括身体虚弱和认知障碍,没有痴呆症.
- 迫切需要对T2DM患者的CF进行早期检测和干预策略.
研究的目的:
- 调查2型糖尿病 (T2DM) 的老年人认知虚弱 (CF) 的患病率.
- 在这个人群中确定与CF相关的独立风险因素.
主要方法:
- 一项横截面研究包括713名年龄≥65岁的T2DM患者.
- 用临床痴呆症评分 (CDR) 评估认知功能.
- 身体虚弱的评估是使用碎的虚弱表型 (FP) 标准;CF被定义为CDR=0.5和FP得分≥3.5.
主要成果:
- 在T2DM患者中,CF的患病率为24.3%.
- 脑血管疾病 (OR: 2.39) 和外围动脉疾病 (OR: 1.74) 是CF的重要危险因素.
- 高等教育 (OR:0.85) 和晚期糖尿病发病 (OR:0.93) 显示有保护作用.
结论:
- 患有T2DM的老年人表现出CF的高风险,特别是那些患有脑血管疾病,外围动脉疾病,低教育或早期发病的糖尿病的人.
- 糖尿病早期发病可能会减少认知储备,突出显示需要主动代谢和血管风险管理.
- 建议在糖尿病护理中对认知和身体虚弱进行综合查,以便及时进行干预.
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