由于Trametes elegans和Peniophora incarnata引起的肺部感染
Hiroo Matsuo1, Kensuke Fujiwara2, Makoto Niki3
1Department of Infection Control and Prevention, Graduate School of Medicine, University of Osaka, Osaka, Japan.
Open forum infectious diseases
|October 13, 2025
概括
本案例研究突出了Trametes elegans和Peniophora incarnata引起的罕见真菌肺感染在免疫功能低下的患者中. 沃里可纳显示出有效性,表明气候变化对机会性真菌病的潜在影响.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 越来越多地使用免疫抑制疗法和器官移植导致新的机会性感染.
- 以前未被认为是人类病原体的环境真菌正在出现.
- 获得性免疫缺陷综合征 (艾滋病) 损害免疫力,增加对感染的易感性.
研究的目的:
- 报告一个罕见的肺部感染病例,由Trametes elegans和Peniophora incarnata引起.
- 为了研究这些真菌的病原性潜力和耐热性.
- 描述临床表现和治疗结果.
主要方法:
- 从患者样本中分子识别真菌物种.
- 在体外评估真菌的耐热性.
- 临床病例报告和治疗反应评估.
主要成果:
- 由Trametes elegans和Peniophora incarnata引起的肺部感染,在患有晚期艾滋病的患者中发现.
- 特拉梅特斯 (Trametes elegans) 展示了耐热性,支持其在人类肺部繁殖的能力.
- 在35°C的温度下,Peniophora incarnata的生长有限.
- 最初用脂质体安波特里辛B治疗是无效的;沃里可纳导致临床改善.
结论:
- 阴茎 (Trametes elegans) 和阴茎 (Peniophora incarnata) 可以在免疫功能低下的人中引起肺部感染.
- 菌类的热耐受性是病原性的一个关键因素.
- 沃里康纳可能是这些罕见的真菌感染的有效治疗选择.
- 气候变化可能会增加这种机会性感染的发生率.
关键词:
艾滋病 艾滋病 艾滋病是什么?尼奥福拉体化器 (Peniophora incarnata) 是一个体化器.优雅的小路 (Trametes elegans) 是一个有趣的小路.气候变化 气候变化 气候变化这是一种真菌性肺炎.更多相关视频
08:50Direct Observation of Phagocytosis and NET-formation by Neutrophils in Infected Lungs using 2-photon Microscopy
Published on: June 2, 2011
21.3K
06:43Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
Published on: January 13, 2016
9.3K
相关概念视频
01:28Fungal Phylum Microsporidia
422
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
422
01:30Pneumonia I: Introduction
728
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
728
01:28Pulmonary Tuberculosis II
1.4K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.4K
01:29Pulmonary Tuberculosis I
827
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
827
01:23Skin Diseases and Disorders
5.2K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.2K
01:29Fungal Group Zygomycota
995
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
995