在非霍奇金淋巴瘤患者的COVID-19后持续性呼吸道症状:一个病例报告
Ilias E Dimeas1, Styliani Papra2, George Dimeas3
1Department of Pulmonology, University Hospital of Larissa, Larissa, GRC.
Cureus
|October 13, 2025
概括
患有持续性COVID后肺部问题的免疫功能低下患者需要广泛的诊断. 及时识别低血和免疫球蛋白替代对恢复至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 免疫功能低下的患者,特别是那些接受抗CD20治疗的患者,面临着持续发烧和肺透的诊断挑战.
- 抗CD20治疗会损害幽默免疫力,增加对感染的易感性,并使COVID-19后的恢复复杂化.
研究的目的:
- 介绍一个非霍奇金淋巴瘤患者在抗CD20治疗中经历复杂的COVID-19后肺部症状的病例.
- 突出SARS-CoV-2感染后免疫功能低下,肺部症状未解决的患者的诊断挑战和治疗策略.
主要方法:
- 一个66岁的男性患有非霍奇金淋巴瘤,接受了欧比努祖马布和莱纳利多米德的病例报告.
- 详细介绍了临床表现,包括支气管镜在内的诊断工作以及治疗过程.
- 使用的皮质类固醇, isavuconazole,抗生素和静脉注射免疫球蛋白.
主要成果:
- 患者在COVID-19后出现了长时间的发烧,咳和双边地面玻璃不透明.
- 被诊断为侵袭性肺性阿斯伯吉洛斯症和严重的低甘球蛋白血症.
- 由于B细胞枯竭,病毒清除受损 (持续的SARS-CoV-2 PCR阳性) 已被证明.
- 通过综合治疗实现了临床,放射和免疫恢复.
结论:
- 广泛的差异诊断对于免疫功能低下的患者具有持续的COVID后肺部症状至关重要.
- 及时识别和治疗低胺球蛋白血症,包括免疫球蛋白替代,对于成功的结果至关重要.
- B细胞枯竭可能导致病毒清除受损和机会性感染,需要警监测和量身定制的治疗.
关键词:
反-cd2020 的情况.在Covid 19中,呼吸障碍 呼吸障碍 呼吸障碍发烧 发烧 发烧免疫功能受损的患者.没有霍奇金淋巴瘤的淋巴瘤.这就是Obinutuzumab.后COVID症状 后COVID症状更多相关视频
09:03Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
5.5K
10:21Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
Published on: September 20, 2024
717
相关概念视频
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.5K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.5K
01:28Pleural Effusion II: Symptoms and Management
652
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
652
01:20COPD: Pathogenesis and Clinical Features
1.8K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.8K
01:17Other Pulmonary Disorders
1.5K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.5K
01:31Common Respiratory Disorders
1.3K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.3K
01:22Chronic Obstructive Pulmonary Disease
2.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.2K