从新鲜肉和肉制品中发现抗微生物耐药的Empedobacter的特征
Alba Puente1, José F Cobo-Díaz1,2, Márcia Oliveira1,2
1Department of Food Hygiene and Technology, Universidad de León, León, Spain.
Current research in food science
|October 13, 2025
概括
在肉类中发现的机会性病原体Empedobacter显示出高抗微生物耐药性. 耐卡巴胺菌株携带耐药基因,强调需要监测肉类生产以防止传播抗生素耐药性.
科学领域:
- 微生物学 微生物学
- 抗微生物耐药性 抗微生物耐药性
- 食品安全 食品安全
背景情况:
- 恩佩多巴克 (Empedobacter) 是一种机会性病原体,以多药耐药性而闻名.
- 最后的抗生素正在失去对抗耐药细菌菌株的有效性.
研究的目的:
- 为了鉴定零售肉类中耐卡巴胺耐药的Empedobacter分离物.
- 识别抗菌素耐药性基因 (ARG) 和它们的位置.
主要方法:
- 对62个分离物对15种抗生素进行表型抗微生物敏感性测试.
- 24个分离物的全基因组测序 (WGS) 用于分类学分类和ARG识别.
主要成果:
- 61.3%的Empedobacter菌株具有多药耐药性 (MDR).
- 确定了bla_EBR-1,ere(D) 和tet(X2) 的基因.
- 在E. falsenii.中,tet(X2) 基因经常是等离子体传播的.
结论:
- 肉类中的Empedobacter具有显著的抗菌素耐药性风险.
- 需要对肉类生产系统中的非ESKAPE细菌进行进一步的研究.
- 监测肉类生产对于控制抗生素耐药性的传播至关重要.
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