儿童尿路感染的全球趋势,1990-2021年:GBD研究的结果
Xiepeng Zuo1, Cheng Fang1, Chuanming Wang1
1Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Frontiers in public health
|October 13, 2025
概括
全球儿童尿路感染 (UTI) 病例增加,但整体病例率下降. 然而,在社会人口指数较低的地区,发病率正在上升,这突显了儿童尿路感染负担的差异.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 全球健康 全球健康
- 流行病学 流行病学
背景情况:
- 尿路感染 (UTI) 是儿童常见的泌尿病问题,具有显著的临床影响.
- 本研究研究了从1990年到2021年儿童尿路感染的全球趋势,包括发病率,死亡率和残疾调整寿命年 (DALYs).
研究的目的:
- 从1990年到2021年分析儿童尿路感染发病率,死亡率和DALYs的全球趋势.
- 调查儿童尿路感染负担与社会经济因素之间的关联.
主要方法:
- 利用2021年全球疾病负担 (GBD) 数据,对204个国家的0-14岁儿童进行分析.
- 使用细分和逻辑线性回归进行时间趋势分析和通用添加模型 (GAMs) 来评估与社会人口指数 (SDI) 的关联.
主要成果:
- 全球发生性尿路感染病例增加了10.31%,而发生率在1990-2021年期间下降了4.65%.
- 低SDI地区的发生性尿路感染病例激增63.43%,与SDI较高地区的下降形成鲜明对比.
- 儿童尿路感染负担与社会经济发展和环境条件有关,热带国家发病率较高.
结论:
- 尽管全球发病率有所下降,但近期仍有上升趋势,特别是在社会经济弱势和热带地区.
- 人口之间存在显著的差异,女孩的发病率较高,男孩的死亡率/DALYs较高.
- 根据区域和人口特异性负担进行量身定制的干预措施对于有效预防和治疗儿童尿路感染至关重要.
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