对四种面假肢材料的抗菌性质和表面粗性的比较评估
Zaihan Ariffin1, Yanti Johari1,2, Farhana Rahman1
1School of Dental Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian, Kota Bharu, Kelantan, 16150, Malaysia.
Journal of oral biology and craniofacial research
|October 13, 2025
概括
当地生产的改性聚甲基甲酸 (m-PMMA) 面材料显示微生物粘附性比商业PMMA和少. 这表明m-PMMA可能会降低与假肢设备相关的感染风险.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料 牙科材料
- 微生物学 微生物学
背景情况:
- 微生物粘附于面假肢可以引起感染.
- 假肢材料的抗微生物特性或对微生物粘附的抗性是可取的.
研究的目的:
- 为了比较本地生产的改性聚甲基甲酸盐 (m-PMMA) 与商用聚甲基甲酸盐 (c-PMMA) 和两个弹性体的抗菌作用,表面粗性和微生物粘附性.
- 评估材料对黄金葡萄球菌,突变性菌株菌和白菌的检测.
主要方法:
- 四个材料组进行了测试:m-PMMA,c-PMMA和两个 (A-2000,A-2186).
- 评估了抗菌活性,微生物粘附性 (殖民地形成单位) 和表面粗度.
- 扫描电子显微镜被用来检查表面地形和微生物粘附.
主要成果:
- 没有任何测试材料对评估的微生物表现出抗菌活性.
- 与PMMA (p <0.017) 相比,弹性体显示出黄金葡萄球菌和突变性菌的粘附性显著更高.
- 在和PMMA之间没有发现Candida albicans粘附度的显著差异. 在表面粗度方面,PMMA和弹性体显著不同 (p < 0.05),而是更粗的.
结论:
- 与其他测试材料相比,本地生产的m-PMMA显示微生物粘附性降低.
- m-PMMA中的填充剂可能会影响抗菌剂的释放,从而降低粘附度.
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