心脏衰竭患者营养不良和身体功能的预后意义
Yoshifumi Abe1,2, Yu Horiuchi3, Mitsutoshi Akiho2,4
1Department of Rehabilitation, Faculty of Health Sciences, Tokyo Kasei University Saitama Japan.
Circulation reports
|October 13, 2025
概括
通过控制营养状况 (CONUT) 评分评估的营养不良和通过短物理性能电池 (SPPB) 评分测量的身体功能受损,在心力衰竭 (HF) 患者中存在联系. 营养不良独立地预测HF的不良结果.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 营养不良和身体功能障碍在心力衰竭 (HF) 中很普遍.
- 了解它们的相互作用和预后意义对于患者管理至关重要.
- 这项研究调查了HF患者的营养状况和身体功能之间的关系.
研究的目的:
- 为了检查控制营养状况 (CONUT) 评分和短物理性能电池 (SPPB) 评分在HF患者之间的相关性.
- 为了确定与CONUT和SPPB分数相关的因素.
- 评估营养和身体功能对临床结果的预后影响,包括死亡或HF住院治疗.
主要方法:
- 追溯分析151名HF患者.
- 使用CONUT得分评估营养状况.
- 使用SPPB评分对身体功能进行评估.
- 使用考克斯回归的复合终点的预测分析.
主要成果:
- 在CONUT和SPPB得分之间发现了一个弱但显著的负相关性 (r=-0.214;P=0.008).
- 经过对混因素进行调整后,CONUT评分,但不是SPPB评分,仍然是不利结果的独立预测指标.
- 营养不良 (CONUT ≥5) 独立地与复合终点风险增加2.56倍相关 (aHR 2.56;95% CI 1.46-4.48;P<0.001).
结论:
- 营养不良和身体功能在HF患者中表现出较弱的相关性,具有明显的相关因素.
- 营养不良和身体功能受损都是高频率的预后指标.
- 建议对HF患者进行营养状况和身体功能的常规评估,以预测临床结果.
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