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Updated: Jan 15, 2026

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通过低等级建模以稀疏和密集的残余物进行人眼组织的成像质谱的先进的维度缩小

Roger A R Moens1, Lukasz G Migas1, David M G Anderson2,3

  • 1Delft Center for Systems and Control, Delft University of Technology, Delft 2628 CD, The Netherlands.

Analytical chemistry
|October 13, 2025
PubMed
概括

主要组件追求 (PCP) 和稳定PCP (SPCP) 为成像质谱 (IMS) 数据提供了优越的维度和降低噪声,与传统的主要组件分析 (PCA) 相比. 这些方法有效地处理复杂生物组织中的稀疏信号.

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The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
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