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健康个体中小脑桃体的规范位置:系统审查和元分析

Veeresh Veeresh¹, Mamatha Hosapatna², Girish Menon¹

¹Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

|October 13, 2025

概括

这项研究使用MRI建立了小脑桃体位置的规范性参考,在健康人群中发现麦克雷线上方平均+1.13毫米. 高异质性需要谨慎的解释,临床决策仍然以症状为指导.

科学领域:

神经成像是一种神经成像.
放射学放射学是一门学科.
人体解剖学解剖学解剖学

背景情况:

小脑桃体是脑脊髓成像中的关键地标.
健康个体中小脑桃体位置的规范性数据稀缺且不一致.
确定参考值可以帮助解释在条件,如奇阿里形类型I.

研究的目的:

用MRI测定无症状个体中大脑小桃体相对于麦克雷线的平均位置.
综合来自健康人群的数据,以创建一个标准化的规范基准.
支持在脊图像中进行解剖学解释.

主要方法:

基于MRI的横截面研究的系统审查和元分析.
在PubMed,Embase,Scopus和Web of Science进行的搜索.
使用随机效应模型计算的集中的中小脑桃体位置,并评估异质性 (I2,Tau2,Cochran's Q).
偏差风险使用纽卡斯尔-太华跨部门研究量表 (NOS-xs) 进行评估.

主要成果:

分析了包括3940名健康个体在内的15项研究.
囊桃体的总平均位置在麦克雷线以上为+1.13毫米 (参考区间: -4.67至+6.93毫米).
观察到实质性的异质性 (I2 = 98%),表明现有数据的可变性.
由于研究质量和报告变化,证据的确定性被评为中等.

结论:

综合估计为健康个体中小脑桃体位置提供了规范性参考.
高异质性,中度偏差风险和地理聚类限制了概括性.
发现可以帮助解剖学解释,但临床决策应始终以症状为指导.
未来的研究应该专注于标准化技术和更广泛的采样,以提高诊断相关性.

关键词:

无症状的个体无症状的个体小脑桃体的桃体这就是为什么MRI是MRI.麦克雷线路麦克雷线路规范性数据规范性数据

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