使用CASIA2扫描源前段光学连贯断层扫描仪的虹膜 - 轨道眼接触 (ITC) 指数,对角度闭合进行诊断分析
Ignacio Rodriguez-Una1,2, Gustavo Espinoza3,4, Irene Martínez-Alberquilla5
1Instituto Oftalmológico Fernández-Vega, Avda. Dres. Fernandez-Vega, 34. 33012 , Oviedo, Spain. irodriguezu@fernandez-vega.com.
International ophthalmology
|October 13, 2025
概括
CASIA2 AS-OCT 设备使用虹膜 - 轨道眼接触 (ITC) 指数准确识别角度闭合. 这种方法显示出出色的诊断性能,并且与视镜在评估前腔角度方面有很好的一致性.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 前段成像前段成像的使用
背景情况:
- 闭角玻璃眼 (angle-closure glaucoma) 是导致视力丧失的一个重要原因.
- 准确诊断闭角是及时干预的关键.
- 阴视镜是当前的黄金标准,但可能是主观的.
研究的目的:
- 使用CASIA2 AS-OCT评估虹膜 - 轨道眼接触 (ITC) 指数的诊断性能.
- 为了比较ITC指数与视镜用于角度接近的确定.
- 评估CASIA2 AS-OCT和视镜之间的协议.
主要方法:
- 使用CASIA2 AS-OCT进行ITC指数测量,分析了135只眼睛.
- 进行了动态视镜,以确定角度关闭 (≥2象限).
- 使用接收器操作特征 (ROC) 曲线分析来确定最佳的ITC切断点.
主要成果:
- 平均ITC指数在闭角眼睛 (34.1%) 与开角眼睛 (3.5%) 相比显著更高.
- 一个ITC切线≥20%产生了0.88的曲线下的面积 (AUC),93.2%的灵敏度和83.5%的特异性.
- 在CASIA2和视镜之间,总体一致度为85.2%.
结论:
- 通过ITC索引,CASIA2 AS-OCT显示出通过ITC索引进行角度接近评估的优异诊断性能.
- 该ITC指数显示适度同意视镜,提供精确的前腔角度信息.
- 这项技术提供了一个有前途的,客观的方法来评估近角.
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