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与IgG4相关的脏疾病:从脏组织病理学和免疫病原生成到新的药理干预措施

Eva Baier1, Augusto Vaglio2,3

  • 1Department of Nephrology and Rheumatology, University Medical Center of Goettingen, Goettingen, Germany.

Expert review of clinical immunology
|October 13, 2025
PubMed
概括

免疫球蛋白G4 (IgG4) 相关的病 (IgG4-RKD) 涉及复杂的免疫反应和纤维化. 本综述涵盖IgG4-RKD病理学和针对B细胞和T细胞的新疗法,用于未来的综合治疗策略.

关键词:
B细胞的枯竭导致B细胞的枯竭.针对B细胞的向疗法与IgG4相关的疾病与IgG4相关的脏疾病与IgG4相关的膜性脏病.在IgG4 - 管腔间歇性炎中.这是一种纤维炎症状况.纤维化 纤维化调节协同刺激的调节.

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