解释异质性:成人注意力缺陷/多动症障碍的潜在形状
Laura M McGuigan1, Mary U Simons1, Samantha T Mengwasser1
1Psychology Department, Marquette University, Milwaukee, WI, USA.
成年ADHD在目前的亚型之外提出了各种各样的挑战. 潜在的个人资料分析确定了四个不同的患者亚组,揭示了显著的认知和情感异质性,以改善治疗.
科学领域:
- 神经心理学 神经心理学
- 精神病学是一个精神病学.
- 数据科学数据科学数据科学
背景情况:
- 成年注意力缺陷/多动障碍 (ADHD) 具有多种神经认知,心理和功能障碍的特征.
- 目前的ADHD分类不能完全捕捉成年人面临的挑战的多样性.
研究的目的:
- 通过使用隐性个人资料分析,识别成年患者的不同亚组,推进行ADHD评估.
- 在考虑性能有效性之后,检查这些子组的稳定性.
主要方法:
- 对259名正在接受ADHD评估的成年患者的数据进行了潜质分析.
- 评估了行为,心理和神经心理功能.
- 之前和之后进行了分析,排除了未通过性能有效性测试 (PVTs) 的参与者.
主要成果:
- 出现了四个不同的潜在类别:神经精神病患,仅相对认知低效,保持警的相对认知低效和神经精神病学弹性.
- 患有多动症诊断的可能性在不同班级之间有所不同 (61.6%80%).
- 任务参与度有显著差异,从59.3%到98.0%不等,在PVT排除后,隐性类保持稳定.
结论:
- 成年ADHD患者的不同小组在认知,情感和行为功能方面表现出显著的异质性.
- 识别这些子组可以提高临床病例的概念化.
- 这种方法可能会导致针对成人多动症的更为定制和有效的治疗建议.
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