痴呆症患者的自杀企图和相关因素:台湾为期7年的基于人口的队列研究
Chih-Ching Liu1, Chien-Hui Liu2, Ming-Chung Ko3
1Department of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan.
Journal of affective disorders
|October 13, 2025
概括
痴呆症患者面临更高的自杀企图的风险,特别是在诊断后的第一年. 关键的风险因素包括男性性别,年龄较大,收入较低,以及同时出现的精神疾病,性别之间观察到不同的模式.
科学领域:
- 老年学是一门学科.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 痴呆症患者表现出自杀企图的风险增加.
- 关于亚洲痴呆症人群自杀企图风险因素的证据有限.
研究的目的:
- 检查与台湾痴呆症患者自杀尝试相关住院相关的社会人口统计学和临床因素.
- 在分析中将死亡视为竞争风险.
主要方法:
- 利用台湾国家健康保险研究数据库识别了266,590名年龄≥40岁的新诊断痴呆症患者 (2009-2014).
- 跟踪患者直到第一次自杀未遂住院,死亡或2015年底.
- 采用特定原因的危险模型进行风险评估,包括性别特定的分析.
主要成果:
- 自杀企图住院的整体发病率密度为每1000人年1.81,在诊断后的第一年达到顶峰.
- 显著的危险因素包括男性性别,年龄较大,收入较低,主要抑郁症,双相情感障碍,其他精神疾病,较高的并发症得分和频繁的门诊.
- 在这些关联因素的影响中,注意到了性别特异性差异.
结论:
- 痴呆症患者有更高的自杀企图住院的风险,存在不同的特征.
- 预防策略必须考虑到痴呆症诊断的时间和性别特定的风险概况,以减轻这一群体中自杀企图风险.
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