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Updated: Jan 15, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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解码II类PI3K信号:从膜识别到人类疾病

Roberta Rubino1, Gabriele Squillero1, Lorenzo Prever1

  • 1University of Turin. Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center "Guido Tarone", Via Nizza 52, 10126. Turin, Italy.

Biochimica et biophysica acta. Molecular and cell biology of lipids
|October 13, 2025
PubMed
概括

二等级的酸酸3-激酶 (PI3Ks) 是重要的脂类激酶,调节细胞信号和膜贩运. 它们的失调与癌症和代谢障碍等疾病有关,突出显示了它们的治疗潜力.

关键词:
细胞信号传递 细胞信号传递第二类PI3Ks.类酸盐的含量是多少?

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