诺比 (NOB) 纳米粒子改善了老鼠慢性悖论性睡眠剥夺 (PSD) 诱导的认知缺陷

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Updated: Jan 15, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
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A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

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Yujie Hu1, Dan Hou1, Shuling Wang1

  • 1Department of Neurology, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou, China.

Cell death discovery
|October 13, 2025
PubMed
概括

诺比丁纳米颗粒通过将微质转移到抗炎状态,改善了睡眠剥夺的老鼠的认知能力. 这涉及调节BMAL1/SIRT1/E2F1通路,提供了一个新的治疗策略.

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