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Updated: Jun 15, 2026

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人类牛皮和表皮特异性Ube2l3缺乏的小鼠的单细胞转录组突出显示CXCL16/CXCR6参与牛皮的发展

Xue-Yan Chen1, Li-Ran Ye1, Ni-Chang Fu1

  • 1Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Nature communications
|October 13, 2025
PubMed
概括

UBE2L3作为牛皮的保护生物标志物,抑制皮肤细胞中IL-17A的产生. 它的减少激活炎症通路,导致牛皮病变.

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