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Updated: Jan 15, 2026

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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Published on: February 8, 2018

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Munc13-4通过调节PD-L1的分类和分泌,通过外体调节瘤免疫逃避

Chuqi Liu1, Dexiang Liu1, Xiang Zheng1

  • 1Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.

Nature communications
|October 13, 2025
PubMed
概括

瘤细胞使用带有PD-L1的外体来逃避免疫攻击. 研究人员发现,Munc13-4蛋白控制着这个过程,为癌症免疫治疗提供了一个新的目标.

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