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移除前列腺素会增加微质激活,并加速子进展

Bei Li1, Yiyue Shi1, Wenyu Hou1

  • 1School of Basic Medical Sciences, State Key Laboratory of Brain Function and Disorders, Fudan University, Dong'An Rd 130, Shanghai, 200032, China.

Acta neuropathologica communications
|October 14, 2025
PubMed
概括

进子素 (PGRN) 缺乏通过促进有害的微质激活来加速普里昂疾病. 增强PGRN可能为子和其他神经退行性疾病提供神经保护疗法.

关键词:
微质细胞中的微质细胞神经退行发生神经退行.神经炎症是一种神经炎症.普里翁病是普里翁病的一种疾病.益格拉努林是一种Progranulin.

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