在患有OSAS的患者中,使用斑点追踪心电回声学进行心肌层特异性和异步分析
Jian Huang1, Yan Chen1, Yanni Wu1
1Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, P.R. China.
Acta cardiologica
|October 14, 2025
概括
阻塞性睡眠呼吸暂停综合征 (OSAS) 患者表现出亚临床心肌功能障碍, LV 壁层减少,严重病例中异步增加,尽管射出分数正常. 这突显了OSAS早期心脏变化.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 生物医学工程 生物医学工程
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 与心血管并发症有关.
- 在OSAS患者中,亚临床心肌功能障碍可能会先于明显的心力衰竭.
- 评估心肌层特定的功能和异步,可以揭示早期的心脏变化.
研究的目的:
- 评估在正常LV射出分数 (LVEF) 的OSAS患者中亚临床左心室 (LV) 心肌功能障碍.
- 分析心肌层特定的功能和OSAS中的异步.
- 为了研究OSAS患者的诺拉上腺素 (NE) 水平的变化.
主要方法:
- 32名OSAS患者 (中度/重度) 和20名对照人接受了心声回声扫描.
- 进行了心肌层特异性和异步分析.
- 测量了上腺素 (NE) 水平.
主要成果:
- 与对照组相比,OSAS患者的BMI,DBP和NE水平较高.
- 患有OSAS的患者显示LV后壁变厚,LV质量指数增加.
- 在OSAS组中,LV心肌层降低;严重的OSAS表现出缩失调 (PSD) 的增加和时间到峰值 (TTP) 的缩短.
结论:
- 尽管LVEF正常,但OSAS患者表现出LV心肌壁层的减少.
- 与对照组相比,严重的OSAS与早期的心肌缩失调有关.
- 这些发现表明,在OSAS.中存在亚临床心肌功能障碍.
关键词:
不同步和异步是不同的.左心室喷射分数的部分.心肌功能障碍是指心肌功能障碍.特定于心肌层的心肌层.阻塞性睡眠呼吸暂停综合征斑点跟踪回声心脏图谱 (speckle-tracking echocardiography) 是一种跟踪斑点的回声心脏图谱.更多相关视频
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