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Updated: Jan 15, 2026

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse
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DB-OTO基因疗法治疗遗传性聋症

Vassili Valayannopoulos1, Manohar Bance2, Daniela S Carvalho3

  • 1Regeneron Pharmaceuticals, Tarrytown, NY.

The New England journal of medicine
|October 14, 2025
PubMed
概括

基因疗法DB-OTO改善了与奥托弗林 (OTOF) 相关的儿童耳聋的听力. 这种治疗使许多人能够自然地听到声音,有些人达到正常的听觉敏感度.

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