在COVID-19后,左心室射出小部分长期下降的风险增加
Roham Hadidchi1, Ekram Ali1, Hannah Piskun1
1Department of Radiology Montefiore Health System and Albert Einstein College of Medicine Bronx NY USA.
Journal of the American Heart Association
|October 14, 2025
概括
COVID-19幸存者面临长期左心室射出分数 (LVEF) 降低的更高风险,特别是那些住院的人. 对这些患者来说,心脏监测至关重要,以防止进一步的心脏功能障碍.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19与心血管并发症有关,但对左心室功能的长期影响尚不清楚.
- 调查SARS-CoV-2感染与左心室喷射率 (LVEF) 减少之间的关联至关重要.
研究的目的:
- 为了确定SARS-CoV-2感染是否会增加LVEF下降的风险.
- 评估COVID-19疫苗接种是否减轻了LVEF下降的风险.
主要方法:
- 对患有COVID-19和正常基线LVEF (≥50%) 的患者进行了回顾性研究,并进行了随访心声图 (2016-2024).
- 结果包括LVEF下降到<50%,<40%和<30%.
- 多变量考克斯模型根据人口统计,并发病,疫苗接种情况和基线LVEF进行调整.
主要成果:
- 与对照组相比,COVID-19患者的平均随访LVEF较低,LVEF下降率较高.
- 住院和非住院COVID-19患者均显示LVEF<50%的风险增加. 住院患者的LVEF风险明显更高<40%和<30%.
- 接种疫苗状态与LVEF下降没有显著关联. 热波宁和D-二次体等生物标志物预测住院患者的风险更大.
结论:
- SARS-CoV-2 感染与长期的 LVEF 降低有关,特别是在住院患者中.
- 建议对COVID-19幸存者进行警的心脏监测,以减轻渐进的心脏功能障碍.
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