对患有人类免疫缺陷病毒的人的心脏发现的评估
Sevgi Özan Köse1, Yalın Tolga Yaylalı2, Yiğit Davutoğlu2
1Department of Infection Diseases and Clinical Microbiology, Kars Harakani State Hospital, Kars, Türkiye.
Anatolian journal of cardiology
|October 14, 2025
概括
心血管疾病 (CVD) 在艾滋病毒感染者 (PWH) 中正在增加. 心声学标志物,如腹腔间隔膜厚度,后壁厚度,E/E等.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医疗成像医学成像
背景情况:
- 抗逆转录病毒疗法减少了艾滋病毒感染者 (PWH) 的机会性感染和恶性瘤.
- 然而,心血管疾病 (CVD) 的患病率在PWH中正在增加.
- 在PWH中早期发现心血管疾病对于及时干预至关重要.
研究的目的:
- 调查艾滋病毒 (PWH) 感染者早期心血管疾病 (CVD) 标志物.
- 评估在休息和运动期间的胸前回声心脏成像 (TTE) 在PWH中检测心血管疾病的实用性 (6分钟步行测试[6-MWT]) .
- 评估特定的回声心脏学参数,包括心室间隔膜 (IVS) 厚度,后壁 (PW) 厚度,E/e'比率和肺脉冲过渡时间 (pPTT).
主要方法:
- 一项涉及艾滋病毒感染者 (PWH) 和健康对照者的前性研究.
- 胸前回声心电图 (TTE) 在休息状态下进行,并在6分钟步行测试 (6-MWT) 后立即进行.
- 对人口统计数据,实验室结果和回声心脏学参数的分析,包括IVS厚度,PW厚度,E/e'比率和ppTT.
主要成果:
- 与对照组相比,PWH表现出明显更厚的腹腔间隔膜 (IVS) 和后壁 (PW).
- 肺脉冲过渡时间 (pPTT) 在PWH显著减少 (127.5 ms与457 ms相比).
- 在PWH的6MWT之后,E/e'比率显著增加. 在较低CD4+计数的PWH中观察到更高的E/e'比率,这表明免疫状况和扩张功能障碍之间的相关性.
结论:
- 腹腔间隔膜厚度,后壁厚度,E/e'比率和ppTT是PWH中心血管疾病的潜在早期标志物.
- 透析指数的变化,特别是E/e'比率,可能反映疾病进展,并受到CD4+计数的影响.
- 在PWH中,ppTT对评估肺血管状况和右心室功能有前途,需要进一步研究.
更多相关视频
相关概念视频
Myocarditis III: Medical Management
174
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
174
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
482
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
482
Myocarditis II: Clinical Features and Diagnostic Tests
265
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
265
Imaging Studies for Cardiovascular System III: X-Ray
466
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
466
Immunodeficiency Diseases
2.0K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
2.0K
Heart Failure IV: Classification and Diagnostic Evaluation
319
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
319


