儿科肺外流 - 一个20年的临床叙述
Leonie Bregy1, Philipp K A Agyeman1, Andrea Duppenthaler1
1Division of Paediatric Infectious Disease, Department of Paediatrics, Bern University Hospital, Inselspital, University of Bern, Bern, CH-3010, Switzerland.
Infection
|October 14, 2025
概括
儿科副肺喷液 (PPE) 管理已经发展,更多地使用肺部排水和更短的抗生素疗程. 在带有PPE的儿童中,Streptococcus pneumoniae会比Streptococcus pyogenes引起更多的肺损伤.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
背景情况:
- 儿科肺外流 (PPE) 携带了败血症和肺部继发症的风险.
- 目前缺乏个人防护设备的治疗指南.
- 管理策略各不相同,影响患者的治疗结果.
研究的目的:
- 分析个人防护设备管理的趋势随着时间的推移.
- 评估管理策略对短期结果的影响.
- 为了比较由不同的病原体引起的PPE的临床差异.
主要方法:
- 追溯观察单中心研究.
- 对2004年至2024年期间入院的255名PPE患者的分析.
- 用于趋势分析的Jonckheere-Terpstra测试.
主要成果:
- 在研究期间,肺排水量从20%增加到65%.
- 静脉注射抗生素的持续时间从15天减少到11天.
- 肺炎链球菌与更大的肺损伤有关,而炎性链球菌与败血症/毒性休克更为相关.
结论:
- 由S. pneumoniae和S. pyogenes引起的PPE之间存在显著的临床差异.
- 肺炎感染导致更严重的肺损伤.
- 不断发展的管理策略可能会影响个人防护设备的结果.
相关概念视频
Pleural Effusion II: Symptoms and Management
652
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
652
Pleural Effusion I: Introduction
3.9K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
3.9K
Pneumonia II: Pathophysiology
2.6K
The pathophysiology of pneumonia involves the following steps:
2.6K
Pneumonia III: Complications and Assessment
786
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
786
Pneumonia V: Nursing management and Prevention
3.4K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.4K
Pneumonia I: Introduction
728
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
728


