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使用TOMAHAQ对MHC-I的有针对性的分析

Marlene L Heberling1, Sam Pollock2, Qui T Phung1

  • 1Proteomic and Genomic Technologies, Genentech, South San Francisco, CA, USA.

Methods in molecular biology (Clifton, N.J.)
|October 14, 2025
PubMed
概括

我们开发了一种半自动化方法来丰富主要基因相容性复合物I类 (MHC-I) ,提高免疫治疗研究的吞吐量和灵敏度. 这种技术使MHC-I体的快速,可重现的分析成为可能,以更好地了解免疫调节.

关键词:
绝对量化 (TOMAHAQ) 是一个方法.精确的质量-质量.关联性净化净化方法癌症免疫学 癌症免疫学高分辨率的高分辨率免疫类药物 免疫类药物主要组织相容性复合物I类 (MHC-I)质谱测量质量谱测量多重复合的 多重复合的新抗原是一种新抗原.半自动化 半自动化 半自动化由偏移引发的触发.

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