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Updated: Jan 15, 2026

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核酸可编程蛋白质阵列用于自身抗体发现:一个逐步指南

Kesari Warnakulasuriya1, Lusheng Song1, Joshua LaBaer2

  • 1Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, USA.

Methods in molecular biology (Clifton, N.J.)
|October 14, 2025
PubMed
概括

本指南详细介绍使用核酸可编程蛋白质阵列 (NAPPA) 来发现和验证疾病的自身抗体生物标志物. 它涵盖实验设计,阵列制造和用于生物标记物识别的数据分析.

关键词:
自动抗体是一种自身抗体.生物标志物生物标志物发现和验证的发现和验证核酸可编程蛋白质阵列 (NAPPA) 是一种质量控制 质量控制

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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