机械功率方程的可复制性在通风的危急病患儿童中
Agnes K Maas1, Jonathan W J Melger2, David M P van Meenen3
1Department of Pediatric Intensive Care, Emma Children's Hospital of the Amsterdam University Medical Centers, Amsterdam, The Netherlands.
概括
三个机械功率 (MP) 方程准确地复制了在侵袭性压力控制通风 (PCV) 中的重症儿童中计算MP的几何方法. 这一发现支持它们在儿科重症监护室 (PICU) 的使用.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 呼吸机械学 呼吸机械
- 机械通风机械通风机械通风
背景情况:
- 精确测量机械功率 (MP) 对于在机械通风上管理危急儿童至关重要.
- 现有的MP方程需要与几何方法等既定方法进行验证.
研究的目的:
- 在接受侵袭性压力控制通风 (PCV) 的儿童中,与几何方法相比,评估三种不同的机械功率 (MP) 方程的可重现性.
主要方法:
- 在一个单一中心的儿科重症监护室 (PICU) 进行了一项前性探索性研究.
- 其中包括37名患有严重疾病的儿童 (年龄<18岁),接受侵入性PCV治疗.
- 三个MP方程 (简化,综合,线性) 与使用Bland-Altman和类内相关系数 (ICC) 分析的几何方法进行了比较.
主要成果:
- 所有三个MP方程都与几何方法有很好的一致性,ICC始终高于0.99 (p < 0.001).
- 方程和几何方法之间的平均差异很小,处于可接受的临床范围内.
- 该研究包括了儿童,平均年龄为12个月.
结论:
- 简化,综合和线性MP方程可靠且可重现,用于计算侵袭性PCV的危急病患儿童的机械功率.
- 这些验证的方程可以在临床实践中用于监测儿科患者的呼吸机制.
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