世界卫生组织的淋巴结,脏和胆小板细胞病理报告系统:第二部分 - - 脏和胆小板细胞病理报告系统
Immacolata Cozzolino1, Mariarita Calaminici2, Andrea Ronchi3
1Pathology Unit, University Hospital A.O.U. Luigi Vanvitelli, Naples, Italy, coimma@yahoo.it.
Acta cytologica
|October 14, 2025
概括
世界卫生组织 (WHO) 系统标准化了胆髓和脏细针吸收活检 (FNAB) 的细胞病理报告. 这种方法有助于诊断,但需要进一步研究才能在临床实践中得到最佳应用.
科学领域:
- 细胞病理学 细胞病理学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 国际细胞学会和国际癌症研究机构开发了世界卫生组织 (WHO) 标准化的淋巴结,脏和胸腺细胞病理报告系统.
- 在成像指导下精细针吸收活检 (FNAB) 是大和胸腺的微创诊断技术.
- 当与快速现场评估和辅助测试 (如流细胞计,免疫细胞化学和分子测试) 相结合时,FNAB是有价值的.
研究的目的:
- 介绍和讨论世卫组织关于胸膜和脏细胞病理的报告系统.
- 为了突出FNAB对胸腺和脏的诊断实用性和挑战.
- 强调需要进一步的研究来完善FNAB的作用和与先进技术的整合.
主要方法:
- 世界卫生组织系统用于分类胸和脏细胞病理的应用.
- 使用超声波或计算机断层扫描指导的细针吸收活检 (FNAB).
- 结合辅助技术,如免疫类型分析和分子测试.
主要成果:
- 世界卫生组织系统将胸膜和脏细胞病理分为五个诊断类别:不充分/不充分/无诊断性,良性,不典型,可疑恶性瘤和恶性.
- 胸腺的FNAB用于诊断大增血症,胸腺瘤,胸腺癌和淋巴瘤,尽管区分可能具有挑战性.
- 脊髓FNAB对于评估脊髓巨变,感染,淋巴瘤和其他瘤有价值,有助于分期和监测.
结论:
- 世卫组织系统为胸膜和脏细胞病理诊断提供了一个协调的,基于证据的框架,增强风险评估和临床决策.
- 关于FNAB对胸腺和脏的适用性仍在争论中,人们对样本的充分性,诊断的准确性和潜在的并发症 (如出血) 仍存在担忧.
- 进一步的研究是必不可少的,以完善FNAB的诊断作用,改善其与分子技术的整合,并优化其在个性化医学中的使用.
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