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Updated: Jan 15, 2026

Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy
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Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy

Published on: June 25, 2013

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毒素在抗原受体基因多样化过程中促进重组忠实性

Alice Billie Libri1, Jinglong Wang2, Timea Marton1

  • 1Institut Pasteur, Université Paris Cité, INSERM U1223, Équipe Labellisée Ligue Contre Le Cancer, Genome Integrity, Immunity and Cancer Unit, 75015 Paris, France.

Science signaling
|October 14, 2025
PubMed
概括

参素 (SETX) 对于准确的V(D) J重组至关重要,这是免疫细胞多样性至关重要的过程. 它的损失损害了DNA修复,导致抗原受体基因组合中的错误.

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