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Updated: May 30, 2026

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
10:44

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

Published on: January 31, 2018

在诊所中对DNA损伤反应进行药物治疗:超越PARP

Carlos Torrado1, Alvaro Gonzalez-Ortiz2, Camila B Xavier1

  • 1Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.

Expert review of anticancer therapy
|October 14, 2025
PubMed
概括

下一代DNA损伤反应 (DDR) 抑制剂显示出超出PARP抑制剂的前景. 本综述涵盖了用于改善癌症治疗的新型DDR目标,生物标志物和组合策略.

关键词:
这是一个ATMATMATM.基因损伤反应 (DDR) 是指对DNA损伤的反应.波兰人 波兰人 波兰人USP1 USP1 的意思是在WEE1中,WEE1是WEE1的代名词.生物标志物 生物标志物临床发展 临床发展合成杀伤性 合成杀伤性

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Visualization and Quantitative Analysis of Genotoxin-Induced PARP1/PARP2 Activation in Cells Using a Fluorescent Fusion Protein-Based Reporter07:53

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