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避孕药和无效疗法效应

Belina Rodrigues¹, Nandini Raghuraman, Roni Shafir

¹Department of Pain and Translation Symptom Science | Placebo Beyond Opinions Center, School of Nursing, University of Maryland, Baltimore, MD, United States.

|October 14, 2025

概括

心理神经生物学,个性化和规范化 (PIN) 框架促进了对安慰剂和无效果效应的理解. 它整合了心理神经生物学,人工智能和数字疗法,用于个性化医疗和主流临床整合.

科学领域:

神经科学是一个神经科学.
心理学心理学心理学
医疗信息学医疗信息学

背景情况:

传统的研究集中在安慰剂和无效果效应的心理神经生物学机制上.
最近的进展包括用于响应预测的AI和用于个性化的数字治疗方法.

研究的目的:

介绍心理神经生物学,个性化和规范化 (PIN) 框架.
概述理解和利用安慰剂/安慰剂效应的阶段性方法.
建议整合到主流医疗实践中.

主要方法:

审查目前在心理神经生物学和人工智能应用领域的研究.
三阶段框架的概念化 (心理神经生物学,个性化,规范化).
关于临床整合战略的建议.

主要成果:

PIN框架将研究和应用分为三个不同的阶段.
确定人工智能和数字疗法是个性化阶段的关键组成部分.
强调在规范化阶段主流整合的潜力.

结论:

PIN框架为安慰剂和nocebo研究提供了一个结构化的方法.
人工智能,数字治疗和预期管理的整合可以个性化治疗.
正常化阶段的目标是将这些见解嵌入常规医疗保健中.

关键词:

临床试验中的临床试验.调整条件调整条件预期是指期望 (expectancy) 是指期望的意思.预期期望预期学习学习学习学习学习疼痛疼痛疼痛疼痛预测者预测者语言建议语言建议

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