COVID-19感染与精神疾病风险之间的关联:系统性审查和元分析
Jiayi Liu1, Honghao Lai1, Weilong Zhao1
1Department of Health Policy and Health Management, School of Public Health, Lanzhou University, Lanzhou, China; Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.
General hospital psychiatry
|October 14, 2025
概括
COVID-19感染与患上精神健康障碍的风险增加40%有关. 这一系统性审查强调了在2019年冠状病毒疾病之后,迫切需要对心理健康保持警.
科学领域:
- 流行病学 流行病学
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- 由于COVID-19的流行,人们对其长期健康后果感到担忧.
- 新出现的证据表明,SARS-CoV-2感染与心理健康问题之间存在潜在联系.
研究的目的:
- 系统地审查和元分析COVID-19与精神疾病风险之间的关联.
- 量化COVID-19后精神健康状况的风险增加.
主要方法:
- 在主要数据库 (PubMed,Embase,CINAHL,PsycINFO) 进行全面的文献搜索.
- 包括28项符合条件的队列研究,参与者超过9.77亿人.
- 随机效应元分析用于计算聚合风险比率和置信区间.
主要成果:
- 与未接触者相比,患有COVID-19的人群中精神疾病风险增加了40% (RR=1.40,95%CI:1.23至1.59).
- 这意味着每1000人中绝对风险差异为31个新增病例.
- 与COVID-19相关的特定心理健康状况包括焦虑,情绪障碍,神经认知障碍,精神病障碍和压力/调整障碍.
结论:
- 在COVID-19和精神疾病风险增加之间存在显著的关联.
- 与COVID-19相关的精神药物处方也得到了注意.
- 在COVID-19感染后对心理健康问题的提高警对于公共健康至关重要.
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