一个多功能聚合诱导的排放探测器:准确量化,现场检测和二氧化硫衍生物的生物成像使用色度和近红外光探测器
Xiaoyan Su1, Ruifeng Zeng1, Xianxian Huang2
1Department of Pharmacy, Guangxi Medical University Cancer Hospital, Nanning, 530021, Guangxi, PR China; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.
Talanta
|October 14, 2025
概括
一个新的光探测器TPE-YD,可以快速和灵敏地检测食品和生物样本中的二氧化硫 (SO2) 衍生物. 这种探测器为准确地在现场监测SO2衍生物提供了一种新的策略.
科学领域:
- 分析化学 分析化学
- 生物化学 生物化学
- 材料科学 材料科学 材料科学
背景情况:
- 二氧化硫 (SO2) 衍生物在生物和食品系统中至关重要.
- 在现场以高灵敏度和速度检测SO2衍生物仍然具有挑战性.
研究的目的:
- 开发一种新的聚合诱导排放 (AIE) 光探测器,用于SO2衍生物.
- 建立一种灵敏和多功能方法,用于在现场检测SO2衍生物.
主要方法:
- 合成了一种新的AIE光探测器TPE-YD,利用分子内电荷转移 (ICT) 机制.
- 通过UV-Vis吸收和光光谱学研究探头对SO2衍生物的反应.
- 在食品样本和生物细胞中验证了探测器的性能,包括基于智能手机的色度测量方法.
主要成果:
- TPE-YD在强烈的近红外光下表现出明显的AIE效应.
- 吸收和光强度的显著下降与SO2衍生物度线性相关 (R2 = 0.994).
- 实现高灵敏度,检测极限 (LOD) 为基于溶液的检测61nM,基于智能手机的检测为57nM.
结论:
- TPE-YD是一种高度敏感和特定的光探针,用于SO2衍生物.
- 开发的方法允许在真实样本和生物体中进行准确,快速和方便的现场检测.
- 本研究提出了一种新的策略,用于监测SO2衍生物在各种应用中.
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