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Updated: Jan 15, 2026

The Use of Mouse Mammary Tumor Cells in an In Vitro Invasion Assay as a Measure of Oncogenic Cell Behavior
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结合蛋白1通过通过p21依赖的AUF1-ARE调节轴破坏MMP2mRNA的稳定性来抑制瘤入侵

Yulei Wang1, Wenhang Lin1, Yixuan Liao1

  • 1Cancer Center, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Biochemical and biophysical research communications
|October 14, 2025
PubMed
概括

结合蛋白1 (SELENBP1) 通过p21和AUF1依赖的途径破坏MMP2mRNA的稳定,从而抑制癌症的侵袭. 恢复这种SELENBP1轴可能为侵袭性癌症提供新的治疗策略.

关键词:
在AUF1中,AUF1是AUF1.这是入侵的入侵.这就是MMP2的MMP2.转录后的监管 转录后的监管结合蛋白 1 结合蛋白 1 结合蛋白在p2121中,

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