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在睡眠治疗测试台上模拟上呼吸道流量限制

Mate Ferencz¹, Rainer Drath², Benno Dömer²

¹Pforzheim University, 75175 Pforzheim, Tiefenbronner Str. 65, Germany; Löwenstein Medical Technology GmbH & Co. KG, 76135 Karlsruhe, Südendstr. 42, Germany.

Journal of biomechanics

|October 14, 2025

概括

一个新的动态门系统为测试睡眠治疗设备提供了更强大和更灵活的平台. 这种先进的模拟方法提高了可重现性,并准确地模拟了患者的空气流限制,提高了设备评估.

科学领域:

生物医学工程生物医学工程
呼吸系统生理学呼吸系统生理学
医疗器械测试医疗器械测试

背景情况:

由于临床研究和当前的测试方法的局限性,评估睡眠治疗设备的有效性是具有挑战性的.
现有的方法,如上呼吸道模拟的Starling电阻,面临着可重现性和材料降解的问题.

研究的目的:

引入一种新的动态门系统,以便在睡眠治疗设备测试中更准确,更可重复地模拟上呼吸道行为.
通过提供实时控制和灵活性,克服当前模拟技术的局限性.

主要方法:

开发一种由数学电阻模型控制的动态门系统.
使用临界压力参数实时调整上呼吸道阻塞.
模拟各种流量限制波形,反映患者的解剖变异.

主要成果:

该系统展示了对空气流限制的高度控制,从没有到完全阻塞.
与计算机模拟相比,基板验证显示,与计算机模拟相比,正常化根平均平方误差低于4%.
该系统准确地复制了在真实患者中观察到的流量限制模式.

结论:

拟议的动态门系统为评估睡眠治疗设备提供了一个更强大,更灵活和更全面的平台.
提高可重现性和减少对材料特性的依赖性提高了设备测试的可靠性.
该系统的数学框架和适度的硬件要求促进了广泛采用.

关键词:

测试台测试是对测试台进行测试的.模拟模拟是为了模拟.睡眠呼吸暂停 (Sleep Apnea) 是一种疾病.上空气道上空气道上空气道.上空气道阻力上空气道阻力

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